With the new DCL focused on the Rules of Life, there will be a need for cyberinfrastructure and innovative tool support for integrating diverse types of biological data that crosses biological scales of analysis. integration. DBI has several programs that can provide the infrastructure and training for contemporary research in biology. See below for more information.
In 2016, NSF Director France Córdova unveiled ten “Big Ideas” to shape NSF’s priorities for investment at the frontiers of science and engineering, and drive American science into the future. One in particular – “Understanding the Rules of Life” – has reshaped how we within the BIO Directorate think about scientific inquiry in the biological sciences. The Rules of Life Big Idea seeks discoveries that will allow us to accurately predict and understand change and outcomes in biological systems, and to develop infrastructure and innovative tools to help us ask more complex questions than ever before.
NSF has now published a Dear Colleague Letter (“DCL”; NSF 18-031) catalyzed by this Big Idea, titled, “Rules of Life: Forecasting and Emergence in Living Systems.” This DCL solicits research and conference proposals to develop a better understanding of complex interactions within biological systems, and identify causal, predictive principles that operate across scales, levels of organization and layers of complexity – so-called “rules” for how life functions.
This DCL describes an initial opportunity to identify areas where such rules may exist, to drive progress toward their discovery, and to focus efforts on using these rules for prediction and design of biological systems. Activities supported through this DCL include conferences, EArly-concept Grants for Exploratory Research (EAGERs) and Research Advanced by Interdisciplinary Science and Engineering (RAISE) grants to create opportunities for enabling predictive capability.
The knowledge, infrastructure and human capital that will be needed to successfully address such complex questions and identify Rules of Life will require convergence of research across many disciplines. As a result, Directorates across NSF are participating in this DCL, including BIO, Computer and Information Science and Engineering (CISE), Education and Human Resources (EHR), Engineering (ENG), Geosciences (GEO), Mathematical and Physical Sciences (MPS) and Social, Behavioral and Economic Sciences (SBE). Consequently, interdisciplinary and collaborative research proposals are welcomed under this DCL.
Questions? Comments? Feedback? Email RoLBIO@nsf.gov.