NEON completed construction and became fully operational in early 2019. The NSF BIO Directorate has issued a Dear Colleague Letter expanding on its interest in developing and supporting the National Ecological Observatory Network (NEON) user community. The letter details NSF’s plans to issue awards supporting the use of NEON data, including NEON user workshops and conferences, research coordination network awards, and support through the Macrosystems Biology and NEON-Enabled Science Program and other existing programs. BIO plans to provide support for other activities that enable NEON-based research through fostering team science, user group coordination, and new NEON-fueled scientific collaborations. These NEON user community activities are anticipated to be highly complementary to, but distinct from the NEON facility, and are intended to help fully realize the open science mission of NEON.